AMPD1 Antibody

• Background:

  Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

• NCBI Gene ID:

  270

• Swiss Prot:

  P23109

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human AMPD1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HT-29

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 80kDa

• Fragment:

  IgG

• Symbol:

  AMPD1

• Positive Control 2:

  Mouse skeletal muscle

• Positive Control 3:

  Mouse thymus

• Positive Control 4:

  Mouse pancreas

• NCBI Official Name:

  Adenosine monophosphate deaminase 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  AMPD1, adenosine monophosphate deaminase 1 (isoform M), MAD, MADA, Adenosine monophosphate deaminase-1 (muscle), OTTHUMP00000059283, MMDD

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid