AARS Antibody

• Background:

  The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.

• NCBI Gene ID:

  16

• Swiss Prot:

  P49588

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human AARS

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  HepG2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 107kDa

• Fragment:

  IgG

• Symbol:

  AARS

• Positive Control 2:

  SW620

• Positive Control 3:

  U-251MG

• Positive Control 4:

  HeLa

• Positive Control 5:

  MCF7

• Positive Control 6:

  Mouse liver

• NCBI Official Name:

  Alanyl-tRNA synthetase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  AARS, CMT2N

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid