DARS2 Antibody

• Background:

  The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL) .

• NCBI Gene ID:

  55157

• Swiss Prot:

  Q6PI48

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 406-645 of human DARS2 (NP_060592.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  NCI-H460

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 74kDa

• Fragment:

  IgG

• Symbol:

  DARS2

• Positive Control 2:

  U-251MG

• Positive Control 3:

  MCF7

• Positive Control 4:

  BT-474

• Positive Control 5:

  Mouse liver

• Positive Control 6:

  Mouse heart

• NCBI Official Name:

  Aspartyl-tRNA synthetase 2, mitochondrial

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ASPRS, LBSL, MT-ASPRS, mtAspRS, aspartate--tRNA ligase, mitochondrial, aspartate tRNA ligase 2, mitochondrial, aspartyl-tRNA synthetase, mitochondrial

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid