BCS1L Antibody

• Background :

  This gene encodes a homolog of the S. cerevisiae bcs1 protein which is involved in the assembly of complex III of the mitochondrial respiratory chain. The encoded protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria. Mutations in this gene are associated with mitochondrial complex III deficiency and the GRACILE syndrome. Several alternatively spliced transcripts encoding two different isoforms have been described.

• NCBI Gene ID :

  617

• Swiss Prot :

  Q9Y276

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 33-240 of human BCS1L (NP_004319.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Neuroscience, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  HepG2

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 48kDa

• Fragment :

  IgG

• Symbol :

  BCS1L

• Positive Control 2 :

  SKOV3

• Positive Control 3 :

  MCF7

• Positive Control 4 :

  HeLa

• Positive Control 5 :

  Mouse heart

• Positive Control 6 :

  Mouse liver

• NCBI Official Name :

  BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  BCS, BCS1, BJS, FLNMS, GRACILE, Hs.6719, MC3DN1, PTD, h-BCS, h-BCS1, mitochondrial chaperone BCS1, BC1 (ubiquinol-cytochrome c reductase) synthesis-like, BCS1-like protein, mitochondrial complex III assembly

• Tested Applications :

  WB, IHC, IF

• Physical Properties :

  Liquid