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SPOP Antibody

CAT: 0223-23-060Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-23-060Size:100 µL
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Background
This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.
NCBI Gene ID
20747
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of mouse SPOP (NP_079563.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
BT-474
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 42kDa
Fragment
IgG
Symbol
SPOP
Positive Control 2
Mouse pancreas
NCBI Official Name
Speckle-type BTB/POZ protein
NCBI Organism
Mus musculus
Other Product Names
AI315626, Pcif1, TEF2, speckle-type POZ protein, HIB homolog 1, PDX-1 C-terminal-interacting factor 1
Tested Applications
WB, IHC
Physical Properties
Liquid

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