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BAF250 Antibody

CAT: 0223-23-052Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-23-052Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
93760
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1300-1400 of mouse BAF250 (NP_001074288.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Fragment
IgG
Applications Notes
IF: 1:50 - 1:100
Symbol
ARID1A
NCBI Official Name
AT rich interactive domain 1A (SWI-like)
NCBI Organism
Mus musculus
Other Product Names
1110030E03Rik, BAF250a, Osa1, Smarcf1, AT-rich interactive domain-containing protein 1A, ARID domain-containing protein 1A, AT rich interactive domain 1A (Swi1 like), BAF25BRG1-associated factor 250a, SWI-like protein, SWI/SNF complex protein p27SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1, osa homolog 1
Tested Applications
IF
Physical Properties
Liquid

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