NDUFV2 Antibody

• Background:

  The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19.

• NCBI Gene ID:

  4729

• Swiss Prot:

  P19404

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-249 of human NDUFV2 (NP_066552.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  MCF7

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 27kDa

• Fragment:

  IgG

• Symbol:

  NDUFV2

• Positive Control 2:

  HT-29

• Positive Control 3:

  PC-12

• Positive Control 4:

  Mouse liver

• Positive Control 5:

  Mouse brain

• Positive Control 6:

  Rat liver

• NCBI Official Name:

  NADH:ubiquinone oxidoreductase core subunit V2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CI-24k, MC1DN7, NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial, NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa, NADH dehydrogenase ubiquinone flavoprotein 2, mitochondrial, NADH-ubiquinone oxidoreductase 24 kDa subunit, NADH-ubiquinone oxidoreductase flavoprotein 2, complex I 24kDa subunit, complex I, mitochondrial respitory chain, 24 kD subunit, nuclear-encoded mitochondrial NADH-ubiquinone reductase 24Kd subunit

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid