PTGS1 Antibody

• Background:

  This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  5742

• Swiss Prot:

  P23219

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human PTGS1 (NP_001258094.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Immunology, Innate Immunity, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HL-60

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 69kDa

• Fragment:

  IgG

• Symbol:

  PTGS1

• Positive Control 2:

  A-549

• Positive Control 3:

  HT-29

• Positive Control 4:

  THP-1

• Positive Control 5:

  Mouse lung

• Positive Control 6:

  Mouse liver

• NCBI Official Name:

  Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PTGS1, COX1, COX3, PCOX1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS, PES-1

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid