CAPG Antibody, KO Validated

• Background :

  This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene.

• NCBI Gene ID :

  822

• Swiss Prot :

  P40121

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-348 of human CAPG (NP_001738.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Validation :

  Antibody is Knockout validated.

• Field of Research :

  Cell Cycle, Immunology, Innate Immunity, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  THP-1

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 38kDa

• Fragment :

  IgG

• Symbol :

  CAPG

• Positive Control 2 :

  HL-60

• Positive Control 3 :

  Mouse lung

• Positive Control 4 :

  Mouse spleen

• Positive Control 5 :

  Rat heart

• Positive Control 6 :

  Rat lung

• NCBI Official Name :

  Capping protein (actin filament), gelsolin-like

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  CAPG, capping protein (actin filament), gelsolin-like, AFCP, MCP, actin regulatory protein CAP-G, actin-regulatory protein CAP-G, gelsolin-like capping protein, macrophage capping protein, macrophage-capping protein

• Tested Applications :

  WB, IHC

• Physical Properties :

  Liquid