PTPRE Antibody

CAT: 0223-22-786Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-22-786Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels.
NCBI Gene ID
5791
Swiss Prot
P23469
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human PTPRE (NP_006495.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
HL-60
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 81kDa
Fragment
IgG
Symbol
PTPRE
Positive Control 2
SW620
Positive Control 3
Mouse brain
Positive Control 4
Mouse spleen
Positive Control 5
Mouse lung
Positive Control 6
Rat brain
NCBI Official Name
Protein tyrosine phosphatase, receptor type, E
NCBI Organism
Homo sapiens
Other Product Names
PTPRE, DKFZp313F1310, HPTPE, PTPE, R-PTP-EPSILON
Tested Applications
WB, IHC
Physical Properties
Liquid

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