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ELAC2 Antibody

CAT: 0223-22-724Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-22-724Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
60528
Swiss Prot
Q9BQ52
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ELAC2 (NP_776065.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 105kDa
Fragment
IgG
Symbol
ELAC2
Positive Control 2
NCI-H460
NCBI Official Name
ElaC ribonuclease Z 2
NCBI Organism
Homo sapiens
Other Product Names
ELAC2, ElaC (E. coli) homolog 2, ElaC homolog 2 (E. coli), ELC2, ElaC homolog protein 2, HPC2, RNase Z 2, Ribonuclease Z 2, TRNA 3 endonuclease 2, TRNase Z (long form), TRNase Z 2
Tested Applications
WB, IHC, IF
Physical Properties
Liquid

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