NDE1 Antibody

• Background :

  This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe mental retardation. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID :

  54820

• Swiss Prot :

  Q9NXR1

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human NDE1 (NP_060138.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Neuroscience

• Purification :

  Affinity purification

• Positive Control :

  HeLa

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 39kDa

• Fragment :

  IgG

• Symbol :

  NDE1

• Positive Control 2 :

  HepG2

• Positive Control 3 :

  SKOV3

• Positive Control 4 :

  MCF7

• Positive Control 5 :

  A673

• Positive Control 6 :

  Mouse heart

• NCBI Official Name :

  NudE neurodevelopment protein 1

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  NDE1, FLJ20101, HOM-TES-87, NUDE, NUDE1, NDE, LIS4

• Tested Applications :

  WB, IHC

• Physical Properties :

  Liquid