HAND2 Antibody

• Background:

  The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.

• NCBI Gene ID:

  9464

• Swiss Prot:

  P61296

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-217 of human HAND2 (NP_068808.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cell Cycle, Neuroscience, Transcription

• Purification:

  Affinity purification

• Positive Control:

  Mouse liver

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 26kDa

• Fragment:

  IgG

• Symbol:

  HAND2

• Positive Control 2:

  Mouse heart

• NCBI Official Name:

  Heart and neural crest derivatives expressed 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  HAND2, DHand, DHAND2, Hed, Thing2, BHLHa26

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid