AP3B1 Antibody

• Background:

  This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  8546

• Swiss Prot:

  O00203

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 895-1094 of human AP3B1 (NP_003655.3) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  SKOV3

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 132kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  AP3B1

• Positive Control 2:

  SW620

• Positive Control 3:

  Mouse liver

• NCBI Official Name:

  Adaptor related protein complex 3 subunit beta 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ADTB3, ADTB3A, HPS, HPS2, PE, AP-3 complex subunit beta-1, AP-3 complex beta-3A subunit, adaptor protein complex AP-3 subunit beta-1, adaptor related protein complex 3 beta 1 subunit, beta-3A-adaptin, clathrin assembly protein complex 3 beta-1 large chain

• Tested Applications:

  WB

• Physical Properties:

  Liquid