AP3D1 Antibody

• Background:

  The protein encoded by this gene is a subunit of the AP3 adaptor-like complex, which is not clathrin-associated, but is associated with the golgi region, as well as more peripheral structures. The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and may be directly involved in trafficking to lysosomes. This subunit is implicated in intracellular biogenesis and trafficking of pigment granules, and possibly platelet dense granules and neurotransmitter vesicles. Defects in this gene are a cause of a new type of Hermansky-Pudlak syndrome.

• NCBI Gene ID:

  8943

• Swiss Prot:

  O14617

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 520-700 of human AP3D1 (NP_003929.4) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  LO2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 110kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  AP3D1

• Positive Control 2:

  U-87MG

• Positive Control 3:

  Mouse kidney

• Positive Control 4:

  Mouse brain

• NCBI Official Name:

  Adaptor related protein complex 3 subunit delta 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ADTD, HPS1hBLVR, AP-3 complex subunit delta-1, AP-3 complex delta subunit, partial CDS, adapter-related protein complex 3 subunit delta-1, adaptor related protein complex 3 delta 1 subunit, delta adaptin, subunit of putative vesicle coat adaptor complex AP-3

• Tested Applications:

  WB

• Physical Properties:

  Liquid