YARS Antibody

• Background :

  Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.

• NCBI Gene ID :

  8565

• Swiss Prot :

  P54577

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human YARS (NP_003671.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Apoptosis, Cell Cycle, Chemokines & Cytokines, Immunology

• Purification :

  Affinity purification

• Positive Control :

  HeLa

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 59kDa

• Fragment :

  IgG

• Symbol :

  YARS

• Positive Control 2 :

  SKOV3

• Positive Control 3 :

  Mouse brain

• Positive Control 4 :

  Mouse skeletal muscle

• Positive Control 5 :

  Rat brain

• NCBI Official Name :

  Tyrosyl-tRNA synthetase

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  YARS, YRS, YTS, TYRRS, CMTDIC

• Tested Applications :

  WB, IP

• Physical Properties :

  Liquid