SETMAR Antibody

CAT: 0223-22-450Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-22-450Size:100 µL
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Background
This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
NCBI Gene ID
6419
Swiss Prot
Q53H47
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human SETMAR (NP_006506.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Fragment
IgG
Symbol
SETMAR
NCBI Official Name
SET domain and mariner transposase fusion gene
NCBI Organism
Homo sapiens
Other Product Names
SETMAR, SET domain and mariner transposase fusion gene, Mar1, HsMar1, METNASE
Tested Applications
WB, IF
Physical Properties
Liquid

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