RAE1 Antibody

• Background:

  Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly (A) -containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

• NCBI Gene ID:

  8480

• Swiss Prot:

  P78406

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-368 of human RAE1 (NP_003601.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Mouse brain

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 40kDa

• Fragment:

  IgG

• Symbol:

  RAE1

• Positive Control 2:

  Mouse spleen

• Positive Control 3:

  Mouse thymus

• Positive Control 4:

  Rat brain

• NCBI Official Name:

  Ribonucleic acid export 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  RAE1, MIG14, MRNP41, Mnrp41, dJ481F12.3, dJ800J21.1

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid