PNKP Antibody

• Background:

  This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.

• NCBI Gene ID:

  11284

• Swiss Prot:

  Q96T60

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 60-320 of human PNKP (NP_009185.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  HL-60

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 57kDa

• Fragment:

  IgG

• Symbol:

  PNKP

• Positive Control 2:

  HepG2

• Positive Control 3:

  Rat liver

• NCBI Official Name:

  Polynucleotide kinase 3'-phosphatase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PNKP, polynucleotide kinase 3'-phosphatase, PNK, polynucleotide kinase 3-prime-phosphatase, MCSZ, EIEE10

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid