PDCD6 Antibody

• Background:

  This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.

• NCBI Gene ID:

  10016

• Swiss Prot:

  O75340

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-191 of human PDCD6 (NP_037364.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  BT-474

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 16kDa

• Fragment:

  IgG

• Symbol:

  PDCD6

• Positive Control 2:

  HeLa

• Positive Control 3:

  SW620

• Positive Control 4:

  HepG2

• Positive Control 5:

  Mouse liver

• Positive Control 6:

  Mouse kidney

• NCBI Official Name:

  Programmed cell death protein 6

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Programmed cell death protein 6, Apoptosis-linked gene 2 protein, Probable calcium-binding protein ALG-2, PDCD6, ALG2

• Tested Applications:

  WB, IHC, IF, IP

• Physical Properties:

  Liquid