PCMT1 Antibody

• Background:

  This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

• NCBI Gene ID:

  5110

• Swiss Prot:

  P22061

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 62-286 of human PCMT1 (NP_001238978.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  MCF7

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 25kDa

• Fragment:

  IgG

• Symbol:

  PCMT1

• Positive Control 2:

  HepG2

• Positive Control 3:

  293T

• Positive Control 4:

  A-431

• Positive Control 5:

  Mouse liver

• Positive Control 6:

  Mouse brain

• NCBI Official Name:

  Protein-L-isoaspartate (D-aspartate) O-methyltransferase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PCMT1, PIMT

• Tested Applications:

  WB, IF, IP

• Physical Properties:

  Liquid