POLR3K Antibody

• Background:

  This gene encodes a small essential subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor. This similarity in sequence is supported by functional studies showing that this subunit is required for proper pausing and termination during transcription. Pseudogenes of this gene are found on chromosomes 13 and 17.

• NCBI Gene ID:

  51728

• Swiss Prot:

  Q9Y2Y1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-108 of human POLR3K (NP_057394.3) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  MCF7

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 12kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  POLR3K

• Positive Control 2:

  SW620

• NCBI Official Name:

  RNA polymerase III subunit K

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  C11, C11-RNP3, My01RPC1RPC11, RPC12.5, DNA-directed RNA polymerase III subunit RPC1DNA-directed RNA polymerase III subunit K, DNA-directed RNA polymerases III 12.5 kDa polypeptide, RNA polymerase III 12.5 kDa subunit, RNA polymerase III subunit C1RNA polymerase III subunit C11, RNA polymerase III subunit CII, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa, polymerase (RNA) III subunit K

• Tested Applications:

  WB

• Physical Properties:

  Liquid