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AGA Antibody

CAT: 0223-22-149Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-22-149Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the N-terminal nucleophile (Ntn) hydrolase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta chains that comprise the mature enzyme. This enzyme is involved in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves asparagine from N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. Mutations in this gene are associated with the lysosomal storage disease aspartylglycosaminuria that results in progressive neurodegeneration. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is subject to proteolytic processing.
NCBI Gene ID
175
Swiss Prot
P20933
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 161-346 of human AGA (NP_000018.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 37kDa
Fragment
IgG
Symbol
AGA
NCBI Official Name
Aspartylglucosaminidase
NCBI Organism
Homo sapiens
Other Product Names
AGU, ASRG, GA, N (4) - (beta-N-acetylglucosaminyl) -L-asparaginase, N4- (N-acetyl-beta-glucosaminyl) -L-asparagine amidase, aspartylglucosylamine deaspartylase, glycosylasparaginase
Tested Applications
WB, IF
Physical Properties
Liquid