RNPC3 Antibody

• Background:

  Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome.

• NCBI Gene ID:

  55599

• Swiss Prot:

  Q96LT9

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 258-517 of human RNPC3 (NP_060089.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 60-75kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  RNPC3

• Positive Control 2:

  293T

• Positive Control 3:

  MCF7

• Positive Control 4:

  Mouse kidney

• Positive Control 5:

  Rat kidney

• NCBI Official Name:

  RNA binding motif protein 4

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  RBM4, DKFZp547K0918, LARK, MGC75138, RBM4A, ZCCHC21, ZCRB3A, RP11-658F2.8

• Tested Applications:

  WB

• Physical Properties:

  Liquid