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NEU1 Antibody

CAT: 0223-22-109Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-22-109Size:100 µL
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Background
The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein') . Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity.
NCBI Gene ID
4758
Swiss Prot
Q99519
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 156-415 of human NEU1 (NP_000425.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse liver
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 45kDa
Fragment
IgG
Symbol
NEU1
Positive Control 2
Rat liver
NCBI Official Name
Sialidase 1 (lysosomal sialidase)
NCBI Organism
Homo sapiens
Other Product Names
NEU1, NEU, SIAL1, NANH
Tested Applications
WB, IHC
Physical Properties
Liquid

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