PLIN2 Antibody

• Background:

  The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene.

• NCBI Gene ID:

  123

• Swiss Prot:

  Q99541

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 168-437 of human PLIN2 (NP_001113.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  SW620

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 48kDa

• Fragment:

  IgG

• Symbol:

  PLIN2

• Positive Control 2:

  HepG2

• Positive Control 3:

  U-87MG

• Positive Control 4:

  Mouse brain

• Positive Control 5:

  Mouse heart

• Positive Control 6:

  Mouse liver

• NCBI Official Name:

  Perilipin 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Perilipin-2, Adipophilin, Adipose differentiation-related protein, ADRP, PLIN2, ADFP

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid