GSK3B Antibody, KO Validated

• Background:

  The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  2932

• Swiss Prot:

  P49841

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human GSK3B (NP_001139628.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Validation:

  Antibody is Knockout validated.

• Field of Research:

  Apoptosis, Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction, Stem Cell

• Purification:

  Affinity purification

• Positive Control:

  LO2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 46kDa

• Fragment:

  IgG

• Symbol:

  GSK3B

• Positive Control 2:

  HeLa

• Positive Control 3:

  22Rv1

• Positive Control 4:

  U-251MG

• NCBI Official Name:

  Glycogen synthase kinase 3 beta

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  GSK3B, GSK-3 beta, GSK3 beta, GSK3beta, GSK3beta isoform, TPKI, GSK 3beta, Tau protein kinase I, ZGSK-3beta

• Tested Applications:

  WB, IF, IP

• Physical Properties:

  Liquid