P4HTM Antibody

• Background :

  The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified.

• NCBI Gene ID :

  54681

• Swiss Prot :

  Q9NXG6

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 294-563 of human P4HTM (NP_808807.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer

• Purification :

  Affinity purification

• Positive Control :

  MCF7

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 55kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:2000

• Symbol :

  P4HTM

• Positive Control 2 :

  Jurkat

• Positive Control 3 :

  293T

• Positive Control 4 :

  U-87MG

• Positive Control 5 :

  HeLa

• Positive Control 6 :

  Mouse heart

• NCBI Official Name :

  Prolyl 4-hydroxylase, transmembrane

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  EGLN4, HIFPH4, P4H-TM, PH-4, PH4, PHD4, transmembrane prolyl 4-hydroxylase, HIF-PH4, HIF-prolyl hydroxylase 4, HPH-4, P4H with transmembrane domain, Prolyl hydroxlase domain-containing 4, hypoxia-inducible factor prolyl 4-hydroxylase, hypoxia-inducible factor prolyl hydroxylase 4, proline 4-hydroxylase, prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)

• Tested Applications :

  WB

• Physical Properties :

  Liquid