PRODH Antibody

• Background:

  This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4) . This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  5625

• Swiss Prot:

  O43272

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 321-600 of human PRODH (NP_057419.4) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cancer, Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  BT-474

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 68kDa

• Fragment:

  IgG

• Symbol:

  PRODH

• Positive Control 2:

  MCF-7

• Positive Control 3:

  U-251MG

• Positive Control 4:

  A-673

• Positive Control 5:

  Mouse liver

• Positive Control 6:

  Mouse kidney

• NCBI Official Name:

  Proline dehydrogenase (oxidase) 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PRODH, tumor protein p53 inducible protein 6, TP53I6, SCZD4, proline oxidase, mitochondrial, proline oxidase 2, proline dehydrogenase, proline dehydrogenase (oxidase) 1, PRODH2, PRODH1, POX, PIG6, p53-induced gene 6 protein, OTTHUMP00000196497, OTTHUMP00000196496, MGC148079, MGC148078, HSPOX2, FLJ33744, POX2

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid