BBOX1 Antibody

• Background:

  This gene encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation.

• NCBI Gene ID:

  8424

• Swiss Prot:

  O75936

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human BBOX1 (NP_003977.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  U-251MG

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 45kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  BBOX1

• Positive Control 2:

  MCF7

• Positive Control 3:

  BT-474

• Positive Control 4:

  Mouse liver

• Positive Control 5:

  Mouse kidney

• Positive Control 6:

  Mouse spinal cord

• NCBI Official Name:

  Butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  BBOX1, BBH, G-BBH, Gamma-BBH, BBOX

• Tested Applications:

  WB

• Physical Properties:

  Liquid