QDPR Antibody

• Background:

  This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.

• NCBI Gene ID:

  5860

• Swiss Prot:

  P09417

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-244 of human QDPR (NP_000311.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Mouse liver

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 26kDa

• Fragment:

  IgG

• Symbol:

  QDPR

• Positive Control 2:

  Mouse kidney

• Positive Control 3:

  Mouse brain

• Positive Control 4:

  Rat liver

• Positive Control 5:

  HL-60

• Positive Control 6:

  BT-474

• NCBI Official Name:

  Dihydropteridine reductase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Dihydropteridine reductase, HDHPR, Quinoid dihydropteridine reductase, QDPR, DHPR

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid