PNMT Antibody

• Background:

  The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline) . The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene.

• NCBI Gene ID:

  5409

• Swiss Prot:

  P11086

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-282 of human PNMT (NP_002677.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience

• Purification:

  Affinity purification

• Positive Control:

  K-562

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 31-34kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  PNMT

• Positive Control 2:

  Mouse liver

• Positive Control 3:

  Mouse heart

• NCBI Official Name:

  Phenylethanolamine N-methyltransferase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PENTase, PNMT, phenylethanolamine N-methyltransferase, noradrenaline N-methyltransferase, phenylethanolamine N-methylase

• Tested Applications:

  WB

• Physical Properties:

  Liquid