APRT Antibody

• Background :

  Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP) . It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID :

  353

• Swiss Prot :

  P07741

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human APRT (NP_000476.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  MCF7

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 20kDa

• Fragment :

  IgG

• Symbol :

  APRT

• Positive Control 2 :

  22Rv1

• Positive Control 3 :

  THP-1

• Positive Control 4 :

  A-549

• Positive Control 5 :

  K-562

• Positive Control 6 :

  HeLa

• NCBI Official Name :

  Adenine phosphoribosyltransferase

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  APRT, AMP, DKFZp686D13177, MGC125856, MGC125857, MGC129961, APRTD

• Tested Applications :

  WB, IF

• Physical Properties :

  Liquid