APRT Antibody

• Background:

  Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP) . It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  353

• Swiss Prot:

  P07741

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human APRT (NP_000476.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  MCF7

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 20kDa

• Fragment:

  IgG

• Symbol:

  APRT

• Positive Control 2:

  22Rv1

• Positive Control 3:

  THP-1

• Positive Control 4:

  A-549

• Positive Control 5:

  K-562

• Positive Control 6:

  HeLa

• NCBI Official Name:

  Adenine phosphoribosyltransferase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  APRT, AMP, DKFZp686D13177, MGC125856, MGC125857, MGC129961, APRTD

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid