ORC6 Antibody

• Background :

  The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.

• NCBI Gene ID :

  23594

• Swiss Prot :

  Q9Y5N6

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-252 of human ORC6 (NP_055136.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Affinity purification

• Positive Control :

  Jurkat

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 28kDa

• Fragment :

  IgG

• Symbol :

  ORC6

• Positive Control 2 :

  SW620

• Positive Control 3 :

  PC-3

• Positive Control 4 :

  HeLa

• Positive Control 5 :

  Mouse brain

• Positive Control 6 :

  Rat brain

• NCBI Official Name :

  Origin recognition complex, subunit 6

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  ORC6L, origin recognition complex, subunit 6 homolog-like (yeast), ORC6, origin recognition complex subunit 6, subunit 6-like (yeast), subunit 6 (yeast homolog) -like, ORC6L

• Tested Applications :

  WB, IF

• Physical Properties :

  Liquid