EEF2K Antibody, KO Validated

• Background :

  This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.

• NCBI Gene ID :

  29904

• Swiss Prot :

  O00418

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 406-725 of human EEF2K (NP_037434.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Validation :

  Antibody is Knockout validated.

• Field of Research :

  Neuroscience, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  HepG2

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 110kDa

• Fragment :

  IgG

• Symbol :

  EEF2K

• Positive Control 2 :

  HeLa

• Positive Control 3 :

  LOVO

• Positive Control 4 :

  22Rv1

• Positive Control 5 :

  293T

• Positive Control 6 :

  Mouse spleen

• NCBI Official Name :

  Eukaryotic elongation factor 2 kinase

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  CaMKIII, HSU9385eEF-2K, eukaryotic elongation factor 2 kinase, alternative protein EEF2K, calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase, calmodulin-dependent protein kinase III, eEF-2 kinase, elongation factor-2 kinase, eukaroytic elongation factor 2 kinase

• Tested Applications :

  WB, IF

• Physical Properties :

  Liquid