CFP Antibody

• Background:

  This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.

• NCBI Gene ID:

  5199

• Swiss Prot:

  P27918

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 190-469 of human CFP (NP_001138724.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Innate Immunity

• Purification:

  Affinity purification

• Positive Control:

  Mouse spleen

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 50kDa

• Fragment:

  IgG

• Symbol:

  CFP

• NCBI Official Name:

  Properdin

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Properdin, Complement factor P, CFP, PFC

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid