WWP1 Antibody

• Background:

  WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined.

• NCBI Gene ID:

  11059

• Swiss Prot:

  Q9H0M0

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human WWP1 (NP_008944.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  PC-3

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 95kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  WWP1

• NCBI Official Name:

  WW domain containing E3 ubiquitin protein ligase 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  AIP5, Tiul1, hSDRP1, NEDD4-like E3 ubiquitin-protein ligase WWP1, HECT-type E3 ubiquitin transferase WWP1, Nedd-4-like ubiquitin-protein ligase, TGIF-interacting ubiquitin ligase 1, WW domain-containing protein 1, atrophin-1 interacting protein 5

• Tested Applications:

  WB

• Physical Properties:

  Liquid