ALS2 Antibody

CAT: 0223-19-493Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-19-493Size:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
57679
Swiss Prot
Q96Q42
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ALS2 (NP_065970.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience
Purification
Affinity purification
Positive Control
Mouse testis
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 174kDa
Fragment
IgG
Symbol
ALS2
Positive Control 2
Mouse thymus
NCBI Official Name
Amyotrophic lateral sclerosis 2 (juvenile)
NCBI Organism
Homo sapiens
Other Product Names
ALS2, amyotrophic lateral sclerosis 2 (juvenile), ALSJ, PLSJ, IAHSP, KIAA1563, ALS2CR6
Tested Applications
WB, IF
Physical Properties
Liquid

Related Products

CatalogName
45-244PALS2 Peptide
42-291ALS Antibody
42-291PALS Peptide
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
22-741COMMD1 Antibody
22-755ADPGK Antibody
22-760DZIP3 Antibody
22-766MAG Antibody

Alternative Products

CatalogName
MBS851862-01ALS2 Antibody

Popular Products