MRM3 Antibody

• Background :

  Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G (1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID :

  55178

• Swiss Prot :

  Q9HC36

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-420 of human MRM3 (NP_060616.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Affinity purification

• Positive Control :

  U-87MG

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 47kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:2000

• Symbol :

  MRM3

• Positive Control 2 :

  HepG2

• Positive Control 3 :

  293T

• NCBI Official Name :

  Mitochondrial rRNA methyltransferase 3

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  RMTL1, RNMTL1, rRNA methyltransferase 3, mitochondrial, 16S rRNA (guanosine (1370) -2'-O) -methyltransferase, 16S rRNA [Gm1370] 2'-O-methyltransferase, RNA methyltransferase like 1, RNA methyltransferase-like protein 1, putative RNA methyltransferase

• Tested Applications :

  WB

• Physical Properties :

  Liquid