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SPA17 Antibody

CAT: 0223-19-463Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-19-463Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.
NCBI Gene ID
53340
Swiss Prot
Q15506
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-151 of human SPA17 (NP_059121.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 17kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
SPA17
Positive Control 2
SW480
Positive Control 3
THP-1
Positive Control 4
Mouse testis
Positive Control 5
Mouse lung
Positive Control 6
Mouse kidney
NCBI Official Name
Sperm autoantigenic protein 17
NCBI Organism
Homo sapiens
Other Product Names
CT22, SP17, SP17-1, sperm surface protein Sp17, cancer/testis antigen 22, sperm protein 17
Tested Applications
WB
Physical Properties
Liquid

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