DYNC2LI1 Antibody

CAT: 0223-19-460Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-19-460Size:100 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that is a component of the dynein-2 microtubule motor protein complex that plays a role in the retrograde transport of cargo in primary cilia via the intraflagellar transport system. This gene is ubiquitously expressed and its protein, which localizes to the axoneme and Golgi apparatus, interacts directly with the cytoplasmic dynein 2 heavy chain 1 protein to form part of the multi-protein dynein-2 complex. Mutations in this gene produce defects in the dynein-2 complex which result in several types of ciliopathy including short-rib thoracic dysplasia 15 with polydactyly (SRTD15) . Alternative splicing results in multiple transcript variants encoding distinct isoforms.
NCBI Gene ID
51626
Swiss Prot
Q8TCX1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-352 of human DYNC2LI1 (NP_001180393.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
U-251MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 38kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
DYNC2LI1
Positive Control 2
Jurkat
Positive Control 3
293T
Positive Control 4
A-549
Positive Control 5
Mouse testis
Positive Control 6
Mouse eye
NCBI Official Name
Dynein cytoplasmic 2 light intermediate chain 1
NCBI Organism
Homo sapiens
Other Product Names
CGI-6D2LIC, LIC3, cytoplasmic dynein 2 light intermediate chain 1
Tested Applications
WB
Physical Properties
Liquid

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