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KIFAP3 Antibody

CAT: 0223-19-403Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-19-403Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
22920
Swiss Prot
Q92845
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human KIFAP3 (NP_055785.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
LO2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 110kDa
Fragment
IgG
Symbol
KIFAP3
Positive Control 2
SH-SY5Y
Positive Control 3
Mouse brain
Positive Control 4
Mouse testis
Positive Control 5
Mouse lung
Positive Control 6
Rat lung
NCBI Official Name
Kinesin associated protein 3
NCBI Organism
Homo sapiens
Other Product Names
FLA3, KAP-1, KAP-3, KAP3, SMAP, Smg-GDS, dJ190I16.1, kinesin-associated protein 3, small G protein GDP dissociation stimulator, smg GDS-associated protein
Tested Applications
WB, IP
Physical Properties
Liquid

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