TRIOBP Antibody

• Background:

  This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD) .

• NCBI Gene ID:

  11078

• Swiss Prot:

  Q9H2D6

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 180-310 of human TRIOBP (NP_008963.3) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  BxPC-3

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 70kDa

• Fragment:

  IgG

• Symbol:

  TRIOBP

• Positive Control 2:

  U-87MG

• Positive Control 3:

  HeLa

• Positive Control 4:

  LO2

• Positive Control 5:

  A-549

• Positive Control 6:

  SW620

• NCBI Official Name:

  TRIO and F-actin binding protein

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  DFNB28, HRIHFB2122, TAP68, TARA, dJ37E16.4, TRIO and F-actin-binding protein, protein Tara, tara-like protein, trio-associated repeat on actin

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid