MUT Antibody

• Background:

  This gene encodes the mitochondrial enzyme methylmalonyl Coenzyme A mutase. In humans, the product of this gene is a vitamin B12-dependent enzyme which catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA, while in other species this enzyme may have different functions. Mutations in this gene may lead to various types of methylmalonic aciduria.

• NCBI Gene ID:

  4594

• Swiss Prot:

  P22033

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 451-750 of human MUT (NP_000246.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  LO2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 83kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:1000 - 1:2000

• Symbol:

  MUT

• Positive Control 2:

  HeLa

• Positive Control 3:

  BT-474

• Positive Control 4:

  22Rv1

• Positive Control 5:

  Mouse liver

• Positive Control 6:

  Mouse kidney

• NCBI Official Name:

  Methylmalonyl-CoA mutase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  MCM, MUT, methylmalonyl-CoA mutase, mitochondrial, methylmalonyl Coenzyme A mutase, methylmalonyl-CoA isomerase, methylmalonyl-CoA mutase c.*192delA, methylmalonyl-CoA mutase c.*51C>G, methylmalonyl-CoA mutase variant c.1495G>A, methylmalonyl-CoA mutase variant c.2011A>G, methylmalonyl-CoA mutase variant c.2150G>T, methylmalonyl-CoA mutase variant c.322C>T, methylmalonyl-CoA mutase variant c.613_615delGAA, methylmalonyl-CoA mutase variant c.636G>A, methylmalonyl-CoA mutase variant c.643G>A, mutant methylmalonyl CoA mutase, truncated methylmalonyl CoA mutase, truncated methylmalonyl-CoA mutase variant c.1420C>T, truncated methylmalonyl-CoA mutase variant c.2179C>T, truncated methylmalonyl-CoA mutase variant c.91C>T

• Tested Applications:

  WB

• Physical Properties:

  Liquid