ACO2 Antibody

• Background:

  The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification.

• NCBI Gene ID:

  50

• Swiss Prot:

  Q99798

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 501-780 of human ACO2 (NP_001089.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 105kDa

• Fragment:

  IgG

• Symbol:

  ACO2

• Positive Control 2:

  U-87MG

• Positive Control 3:

  K-562

• Positive Control 4:

  NIH/3T3

• Positive Control 5:

  Mouse brain

• Positive Control 6:

  Rat spinal cord

• NCBI Official Name:

  Aconitase 2, mitochondrial

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ACO2, ACONM, MGC20605, MGC33908, ICRD

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid