SLC16A2 Antibody

• Background:

  This gene encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2) . This gene is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. This gene is subject to X-chromosome inactivation. Mutations in this gene are the cause of Allan-Herndon-Dudley syndrome.

• NCBI Gene ID:

  6567

• Swiss Prot:

  P36021

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human SLC16A2 (NP_006508.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Growth Factors, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  LO2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 70kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  SLC16A2

• Positive Control 2:

  HT-29

• Positive Control 3:

  293T

• Positive Control 4:

  Mouse heart

• Positive Control 5:

  Mouse kidney

• Positive Control 6:

  Mouse liver

• NCBI Official Name:

  Solute carrier family 16 member 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  AHDS, DXS128, DXS128E, MCT 7, MCT 8, MCT7, MCT8, MRX22, XPCT, monocarboxylate transporter 8, X-linked PEST-containing transporter, monocarboxylate transporter 7, solute carrier family 16, member 2 (thyroid hormone transporter)

• Tested Applications:

  WB

• Physical Properties:

  Liquid