OPCML Antibody

• Background:

  This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. The encoded preprotein is proteolytically processed to generate the mature protein. This protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

• NCBI Gene ID:

  4978

• Swiss Prot:

  Q14982

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 246-345 of human OPCML (NP_002536.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  U-87MG

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 38kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:1000 - 1:2000

• Symbol:

  OPCML

• Positive Control 2:

  293T

• Positive Control 3:

  HeLa

• Positive Control 4:

  Mouse brain

• Positive Control 5:

  Mouse pancreas

• Positive Control 6:

  Mouse kidney

• NCBI Official Name:

  Opioid-binding protein/cell adhesion molecule

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Opioid-binding protein/cell adhesion molecule, OBCAM, OPCML, Opioid-binding cell adhesion molecule, IgLON family member 1, OPCML, IGLON1, OBCAM

• Tested Applications:

  WB

• Physical Properties:

  Liquid