PDCD4 Antibody, KO Validated

CAT: 0223-18-717Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-18-717Size:100 µL
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Background
This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
27250
Swiss Prot
Q53EL6
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PDCD4 (NP_055271.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Apoptosis, Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
MCF-7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 60kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PDCD4
Positive Control 2
HeLa
Positive Control 3
HepG2
Positive Control 4
Mouse thymus
NCBI Official Name
Programmed cell death 4 (neoplastic transformation inhibitor)
NCBI Organism
Homo sapiens
Other Product Names
PDCD4 Antibody: H731, H731, Programmed cell death protein 4, Neoplastic transformation inhibitor protein
Tested Applications
WB
Physical Properties
Liquid

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