PDCD4 Antibody, KO Validated

• Background :

  This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID :

  27250

• Swiss Prot :

  Q53EL6

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PDCD4 (NP_055271.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Validation :

  Antibody is Knockout validated.

• Field of Research :

  Apoptosis, Cancer, Cell Cycle, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  MCF-7

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 60kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:2000

• Symbol :

  PDCD4

• Positive Control 2 :

  HeLa

• Positive Control 3 :

  HepG2

• Positive Control 4 :

  Mouse thymus

• NCBI Official Name :

  Programmed cell death 4 (neoplastic transformation inhibitor)

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  PDCD4 Antibody: H731, H731, Programmed cell death protein 4, Neoplastic transformation inhibitor protein

• Tested Applications :

  WB

• Physical Properties :

  Liquid