PPBP Antibody

• Background:

  The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity.

• NCBI Gene ID:

  5473

• Swiss Prot:

  P02775

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 31-128 of human PPBP (NP_002695.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology, Innate Immunity, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Human serum

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 14kDa

• Fragment:

  IgG

• Symbol:

  PPBP

• NCBI Official Name:

  Platelet basic protein

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Platelet basic protein, PBP, C-X-C motif chemokine 7, Leukocyte-derived growth factor, LDGF, Macrophage-derived growth factor, MDGF, Small-inducible cytokine B7, Connective tissue-activating peptide III, CTAP-III, LA-PF4, Low-affinity platelet factor IV, TC-2, Connective tissue-activating peptide III (1-81), CTAP-III (1-81), Beta-thromboglobulin, Beta-TG, Neutrophil-activating peptide 2 (74), NAP-2 (74), Neutrophil-activating peptide 2 (73), NAP-2 (73), Neutrophil-activating peptide 2, NAP-2, TC-1, Neutrophil-activating peptide 2 (1-66), NAP-2 (1-66), Neutrophil-activating peptide 2 (1-63), NAP-2 (1-63), PPBP, CTAP3, CXCL7, SCYB7, TGB1, THBGB1

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid