PRDX2 Antibody, KO Validated

• Background:

  This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8 (+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.

• NCBI Gene ID:

  7001

• Swiss Prot:

  P32119

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human PRDX2 (NP_859428.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Validation:

  Antibody is Knockout validated.

• Field of Research:

  Cancer, Cell Cycle, Neuroscience

• Purification:

  Affinity purification

• Positive Control:

  SW480

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 20kDa

• Fragment:

  IgG

• Symbol:

  PRDX2

• Positive Control 2:

  22Rv1

• Positive Control 3:

  HepG2

• Positive Control 4:

  K-562

• Positive Control 5:

  BT-474

• Positive Control 6:

  Mouse brain

• NCBI Official Name:

  Peroxiredoxin 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PRDX2, peroxiredoxin 2, HGNC:9353, MGC4104, NKEFB, PRP, PRXII, TDPX1, TSA, natural killer-enhancing factor B, thiol-specific antioxidant 1, thioredoxin peroxidase 1, thioredoxin-dependent peroxide reductase 1, torin

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid